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Article

Thyroid transcription factor-1 (TTF-1/Nkx2.1/TITF1) gene regulation in the lung

28 Nov 2008

Abstract excerpt

TTF-1 [thyroid transcription factor-1; also known as Nkx2.1, T/EBP (thyroid-specific-enhancer-binding protein) or TITF1] is a homeodomain-containing transcription factor essential for the morphogenesis and differentiation of the thyroid, lung and ventral forebrain. TTF-1 controls the expression of select genes in the thyroid, lung and the central nervous system. In the lung, TTF-1 controls the expression of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19037882
DOI: 10.1042/cs20080068

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