Article
Characterization of protocadherin-1 expression in primary bronchial epithelial cells: association with epithelial cell differentiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2012
Koning Henk, Sayers Ian, Stewart Ceri E, de Jong Debora, Ten Hacken Nick H T, Postma Dirkje S, van Oosterhout Antoon J M, Nawijn Martijn C, Koppelman Gerard H
Abstract excerpt
Protocadherin-1 (PCDH1) is a novel susceptibility gene for asthma that is expressed in airway epithelium. We aimed to characterize PCDH1 mRNA transcripts and protein expression in primary bronchial epithelial cells and to determine regulation of PCDH1 during mucociliary differentiation. Total RNA and protein were isolated from human primary bronchial epithelial cells. PCDH1 transcripts were characterized by rapid...
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