Article
Long noncoding RNA TINCR is a novel regulator of human bronchial epithelial cell differentiation state.
Physiological reports - 1 Feb 2021
Omote Norihito, Sakamoto Koji, Li Qin, Schupp Jonas C, Adams Taylor, Ahangari Farida, Chioccioli Maurizio, DeIuliis Giuseppe, Hashimoto Naozumi, Hasegawa Yoshinori, Kaminski Naftali
Abstract excerpt
Long-noncoding RNAs (lncRNAs) have numerous biological functions controlling cell differentiation and tissue development. The knowledge about the role of lncRNAs in human lungs remains limited. Here we found the regulatory role of the terminal differentiation-induced lncRNA (TINCR) in bronchial cell differentiation. RNA in situ hybridization revealed that TINCR was mainly expressed in bronchial epithelial cells...
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