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Article

Myb Permits Multilineage Airway Epithelial Cell Differentiation

8 Aug 2014

Abstract excerpt

The epithelium of the pulmonary airway is specially differentiated to provide defense against environmental insults, but also subject to dysregulated differentiation that results in lung disease. The current paradigm for airway epithelial differentiation is a one-step program whereby a p63(+) basal epithelial progenitor cell generates a ciliated or secretory cell lineage, but the cue for this transition and...

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PMID: 25103188
DOI: 10.1002/stem.1814

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