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Article

Transcriptional Profiling of Mucociliary Differentiation in Human Airway Epithelial Cells

5 Apr 2007

Abstract excerpt

When cultured at an air-liquid interface (ALI) in the appropriate medium, primary human airway epithelial cells form a polarized, pseudostratified epithelium composed of ciliated and mucus-secreting cells. This culture system provides a useful tool for the in vitro study of airway epithelial biology and differentiation. We have performed microarray analysis on ALI cultures of human bronchial epithelial cells...

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PMID: 17413031
DOI: 10.1165/rcmb.2006-0466oc

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