Article
A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancer.
Cancer research - 15 Jun 2004
Halmos Balazs, Bassères Daniela S, Monti Stefano, D'Aló Francesco, Dayaram Tajhal, Ferenczi Katalin, Wouters Bas J, Huettner Claudia S, Golub Todd R, Tenen Daniel G
Abstract excerpt
We showed previously that CCAAT/enhancer binding protein alpha (C/EBP alpha), a tissue-specific transcription factor, is a candidate tumor suppressor in lung cancer. In the present study, we have performed a transcriptional profiling study of C/EBP alpha target genes using an inducible cell line system. This study led to the identification of hepatocyte nuclear factor 3beta (HNF3 beta), a transcription factor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
