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Article

Identification of a novel type 1 diabetes susceptibility gene, T-bet.

Human genetics - 1 Aug 2004

Sasaki Yuka, Ihara Kenji, Matsuura Nobuo, Kohno Hitoshi, Nagafuchi Seiho, Kuromaru Ryuichi, Kusuhara Koichi, Takeya Ryu, Hoey Timothy, Sumimoto Hideki, Hara Toshiro

Abstract excerpt

The gene encoding interferon (IFN)-gamma, IFNG, is known as one of the candidate susceptibility genes for type 1 diabetes. In addition, cytokines, including IFN-gamma, play important roles in the pathogenesis of type 1 diabetes. Therefore, we focused on the Th1-specific T-box transcription factor gene (T-bet), which contributes to the induction of the hallmark Th1 cytokine, IFN-gamma. We first screened for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15241679
DOI: 10.1007/s00439-004-1146-2

Genes

IFNG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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