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Genetic Association of Interleukin 16 Gene Polymorphisms (rs11556218 & rs4778889) with Type 1 Diabetes in Egyptian Children: A Case-Control Study.

Immunological investigations - 1 Jul 2024

Ali Yasser B M, Saed Mai M, Abdel-Hakem Nehal E, Hussein Mona Abd Elmotaleb A, El-Shahat Mohamed

Abstract excerpt

BACKGROUND: Type 1 diabetes (T1D) is a serious chronic autoimmune condition. Even though the underlying reason for the onset of T1D is unknown, due to their effector and regulatory roles in immune responses, cytokines are essential in developing autoimmune disorders. Interleukin (IL)16 is an immunomodulatory cytokine implicated in several inflammatory and autoimmune diseases. OBJECTIVE: This study was designed to...

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PMID: 38771670
DOI: 10.1080/08820139.2024.2349034

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