Article
Increased susceptibility of S100B transgenic mice to perinatal hypoxia-ischemia.
Annals of neurology - 1 Jul 2004
Wainwright Mark S, Craft Jeffrey M, Griffin W Sue T, Marks Alexander, Pineda Jose, Padgett Kyle R, Van Eldik Linda J
Abstract excerpt
S100B is a glial-derived protein that is a well-established biomarker for severity of neurological injury and prognosis for recovery. Cell-based and clinical studies have implicated S100B in the initiation and maintenance of a pathological, glial-mediated proinflammatory state in the central nervous system. However, the relationship between S100B levels and susceptibility to neurological injury in vivo has not...
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