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An increase in reactive oxygen species underlies neonatal cerebellum repair

2024-10-17

Abstract excerpt

The neonatal mouse cerebellum shows remarkable regenerative potential upon injury at birth, wherein a subset of Nestin-expressing progenitors (NEPs) undergoes adaptive reprogramming to replenish granule cell progenitors that die. Here, we investigate how the microenvironment of the injured cerebellum changes upon injury and contributes to the regenerative potential of normally gliogenic - NEPs and their adaptive...

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Literature Corpus work
2b26cd7a-c4a3-53f0-a602-816b9b0bd74f
DOI
10.1101/2024.10.14.618368
Open publication

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An increase in reactive oxygen species underlies neonatal cerebellum repairDOI 10.1101/2024.10.14.618368
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