Article
Progression of reactive gliosis and astroglial phenotypic changes following stab wound-induced traumatic brain injury in mice.
Journal of neurochemistry - 1 Oct 2023
Cieri Maria Belen, Villarreal Alejandro, Gomez-Cuautle Dante Daniel, Mailing Ingrid, Ramos Alberto Javier
Abstract excerpt
Astrocytes are the main homeostatic cells in the central nervous system (CNS) and they have an essential role in preserving neuronal physiology. After brain injury, astrocytes become reactive, and that involves a profound change in the astroglial gene expression program as well as intense cytoskeleton remodeling that has been classically shown by the up-regulation of glial fibrillary acidic protein (GFAP), a...
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