Article
The Rad51/RadA N-terminal domain activates nucleoprotein filament ATPase activity.
Structure (London, England : 1993) - 1 Jun 2006
Galkin Vitold E, Wu Yan, Zhang Xiao-Ping, Qian Xinguo, He Yujiong, Yu Xiong, Heyer Wolf-Dietrich, Luo Yu, Egelman Edward H
Abstract excerpt
Proteins in the RecA/RadA/Rad51 family form helical filaments on DNA that function in homologous recombination. While these proteins all have the same highly conserved ATP binding core, the RadA/Rad51 proteins have an N-terminal domain that shows no homology with the C-terminal domain found in RecA. Both the Rad51 N-terminal and RecA C-terminal domains have been shown to bind DNA, but no role for these domains...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.