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Article

<i>Fgf9</i>induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination

1 Jul 2004

Abstract excerpt

Recently, we demonstrated that loss of Fgf9 results in a block of testis development and a male to female sex-reversed phenotype; however, the function of Fgf9 in sex determination was unknown. We now show that Fgf9 is necessary for two steps of testis development just downstream of the male sex-determining gene, Sry: (1) for the proliferation of a population of cells that give rise to Sertoli progenitors; and...

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Identifiers

PMID: 15229180
DOI: 10.1242/dev.01239

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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