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Article

SRY and the Standoff in Sex Determination

1 Aug 2007

Abstract excerpt

SRY was identified as the mammalian sex-determining gene more than 15 yr ago and has been extensively studied since. Although many of the pathways regulating sexual differentiation have been elucidated, direct downstream targets of SRY are still unclear, making a top down approach difficult. However, recent work has demonstrated that the fate of the gonad is actively contested by both male-promoting and...

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Identifiers

PMID: 17666585
DOI: 10.1210/me.2007-0250

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