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Article

Functional analysis of <i>Sox8</i> and <i>Sox9</i> during sex determination in the mouse

5 Apr 2004

Abstract excerpt

Sex determination in mammals directs an initially bipotential gonad to differentiate into either a testis or an ovary. This decision is triggered by the expression of the sex-determining gene Sry, which leads to the activation of male-specific genes including the HMG-box containing gene Sox9. From transgenic studies in mice it is clear that Sox9 is sufficient to induce testis formation. However, there is no...

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Identifiers

PMID: 15056615
DOI: 10.1242/dev.01087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional analysis of <i>Sox8</i> and <i>Sox9</i> during sex determination in the mousePMID 15056615Read ↗

<i>Sox9</i> in Testis DeterminationSemantic proximity Read ↗

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