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Article

Mixed Signals: Development of the Testis

1 Jan 2009

Abstract excerpt

Induction and patterning of the testis occurs over a brief window of time. Before male-specific morphogenesis, the gonad primordium is bipotential and capable of developing into either an ovary or testis. However, expression of the transcription factor SRY initiates male development and induces patterning, proliferation, and epithelialization specific to the testis. Male sex determination begins with commitment...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 19197800
DOI: 10.1055/s-0028-1108005

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