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Article

Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study.

Diabetes - 1 Jul 2004

Rich Stephen S, Bowden Donald W, Haffner Steven M, Norris Jill M, Saad Mohammed F, Mitchell Braxton D, Rotter Jerome I, Langefeld Carl D, Wagenknecht Lynne E, Bergman Richard N

Abstract excerpt

Genetic and environmental determinants play critical roles in insulin resistance and beta-cell function. A model of the complex feedback system for maintenance of glucose tolerance has been developed that reflects the constraint of glycemia within narrow physiologic limits. The "glucose homeostasis" model is described by insulin sensitivity (S(I)), glucose disposition (S(G)), acute insulin response to glucose...

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Source

Identifiers

PMID: 15220212
DOI: 10.2337/diabetes.53.7.1866

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PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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