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GENOME-WIDE INTERACTION WITH SELECTED TYPE 2 DIABETES LOCI REVEALS NOVEL LOCI FOR TYPE 2 DIABETES IN AFRICAN AMERICANS.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2017

Keaton Jacob M, Hellwege Jacklyn N, Ng Maggie C Y, Palmer Nicholette D, Pankow James S, Fornage Myriam, Wilson James G, Correa Adolfo, Rasmussen-Torvik Laura J, Rotter Jerome I, Chen Yii-DER I, Taylor Kent D, Rich Stephen S, Wagenknecht Lynne E, Freedman Barry I, Bowden Donald W

Abstract excerpt

Type 2 diabetes (T2D) is the result of metabolic defects in insulin secretion and insulin sensitivity, yet most T2D loci identified to date influence insulin secretion. We hypothesized that T2D loci, particularly those affecting insulin sensitivity, can be identified through interaction with known T2D loci implicated in insulin secretion. To test this hypothesis, single nucleotide polymorphisms (SNPs) nominally...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27896979
DOI: 10.1142/9789813207813_0024
PMCID: PMC5146756

Genes

DGKB
CDK18
CXCL12
HCN1
MGMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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