Article
Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study.
Diabetes - 1 Apr 2006
Palmer Nicholette D, Langefeld Carl D, Campbell Joel K, Williams Adrienne H, Saad Mohammed, Norris Jill M, Haffner Stephen M, Rotter Jerome I, Wagenknecht Lynne E, Bergman Richard N, Rich Stephen S, Bowden Donald W
Abstract excerpt
Glucose homeostasis, a defining characteristic of physiological glucose metabolism, is the result of complex feedback relationships with both genetic and environmental determinants that influence insulin sensitivity and beta-cell function. Relatively little is known about the genetic basis of glucose homeostasis phenotypes or their relationship to risk of diabetes. Our group previously published a genome scan for...
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