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Article

Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a conserved fold.

RNA (New York, N.Y.) - 1 Jul 2004

Hoang Charmaine, Ferre-D'Amare Adrian R

Abstract excerpt

The pseudouridine (Psi) synthases Pus7p and TruD define a family of RNA-modifying enzymes with no sequence similarity to previously characterized Psi synthases. The 2.2 A resolution structure of Escherichia coli TruD reveals a U-shaped molecule with a catalytic domain that superimposes closely on that of other Psi synthases. A domain that appears to be unique to TruD/Pus7p family enzymes hinges over the catalytic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15208439
DOI: 10.1261/rna.7240504
PMCID: PMC1370594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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