Article
Discovery of Pyrobaculum small RNA families with atypical pseudouridine guide RNA features.
RNA (New York, N.Y.) - 1 Mar 2012
Bernick David L, Dennis Patrick P, Höchsmann Matthias, Lowe Todd M
Abstract excerpt
In the Eukarya and Archaea, small RNA-guided pseudouridine modification is believed to be an essential step in ribosomal RNA maturation. While readily modeled and identified by computational methods in eukaryotic species, these guide RNAs have not been found in most archaeal genomes. Using high-throughput transcriptome sequencing and comparative genomics, we have identified ten novel small RNA families that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.