Article
Enzymatic characterization and mutational studies of TruD--the fifth family of pseudouridine synthases.
Archives of biochemistry and biophysics - 1 Sept 2009
Chan Chio Mui, Huang Raven H
Abstract excerpt
Pseudouridine (Psi) is formed through isomerization of uridine (U) catalyzed by a class of enzymes called pseudouridine synthases (PsiS). TruD is the fifth family of PsiS. Studies of the first four families (TruA, TruB, RsuA, and RluA) of PsiS reveal a conserved Asp and Tyr are critical for catal...
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