Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pseudouridine-Free Escherichia coli Ribosomes.

Journal of bacteriology - 15 Feb 2018

O'Connor Michael, Leppik Margus, Remme Jaanus

Abstract excerpt

Pseudouridine (Ψ) is present at conserved, functionally important regions in the ribosomal RNAs (rRNAs) from all three domains of life. Little, however, is known about the functions of Ψ modifications in bacterial ribosomes. An Escherichia coli strain has been constructed in which all seven rRNA Ψ synthases have been inactivated and whose ribosomes are devoid of all Ψs. Surprisingly, this strain displays only...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Drug Resistance, Bacterial
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intramolecular Transferases

Share to Nucleic Acid Conformation

Share to Ribosomes

Share to RNA, Ribosomal

Source

Open in PubMed Open full text

Identifiers

PMID: 29180357
DOI: 10.1128/JB.00540-17
PMCID: PMC5786706

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pseudouridine-Free Escherichia coli Ribosomes.PMID 29180357Read ↗

RluA is the major mRNA pseudouridine synthase in <i>Escherichia coli</i>Semantic proximity Read ↗

Conserved Pseudouridines in Helix 69 of the Ribosome are Important for Ribosome Dynamics in TranslationSemantic proximity Read ↗

Inactivation of the RluD pseudouridine synthase has minimal effects on growth and ribosome function in wild-type Escherichia coli and Salmonella enterica.Semantic proximity Read ↗

A pseudouridine synthase required for the formation of two universally conserved pseudouridines in ribosomal RNA is essential for normal growth of Escherichia coli.Semantic proximity Read ↗

Loss of rRNA modifications in the decoding center of the ribosome impairs translation and strongly delays pre-rRNA processing.Semantic proximity Read ↗

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and functionSemantic proximity Read ↗

Quantitative mapping of pseudouridines in bacteria RNASemantic proximity Read ↗

A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma bruceiSemantic proximity Read ↗

16S ribosomal RNA pseudouridine synthase RsuA of Escherichia coli: deletion, mutation of the conserved Asp102 residue, and sequence comparison among all other pseudouridine synthases.Semantic proximity Read ↗

Exploring pseudouridylation: dysregulation in disease and therapeutic potentialSemantic proximity Read ↗

Loss of Conserved rRNA Modifications in the Peptidyl Transferase Center Leads to Diminished Protein Synthesis and Cell Growth in Budding Yeast.Semantic proximity Read ↗

Enzyme-mediated alkynylation enables transcriptome-wide identification of pseudouridine modificationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.