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Article

A common polymorphism in the 5'-untranslated region of the aromatase gene influences bone mass and fracture risk.

European journal of endocrinology - 1 May 2004

Zarrabeitia Maria T, Hernández José L, Valero Carmen, Zarrabeitia Ana L, García-Unzueta Mayte, Amado José A, González-Macías Jesús, Riancho José A

Abstract excerpt

OBJECTIVE: The aromatization of androgenic precursors in peripheral tissues, including bone, is the main source of estrogens after the menopause. CYP19, the gene encoding aromatase, has a long 5'-untranslated region with several variants of exon I and specific promoters. The aim of this study was to investigate the possible relationship between a common biallelic (C/G) polymorphism located on exon I.2 and bone...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15132727
DOI: 10.1530/eje.0.1500699

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A common polymorphism in the 5'-untranslated region of the aromatase gene influences bone mass and fracture risk.PMID 15132727Read ↗

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