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Article

HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity.

AIDS (London, England) - 2 Jul 2004

Lichterfeld Mathias, Yu Xu G, Cohen Daniel, Addo Marylyn M, Malenfant Jessica, Perkins Beth, Pae Eunice, Johnston Mary N, Strick Daryld, Allen Todd M, Rosenberg Eric S, Korber Bette, Walker Bruce D, Altfeld Marcus

Abstract excerpt

OBJECTIVE: To compare the magnitude, breadth and protein specificity of HIV-1-specific CD8 T-cell responses against the clade B consensus sequence during primary and chronic HIV-1 infection and to analyze the impact of viral diversity on the localization of detected responses. METHODS: HIV-1-specific CD8 T-cell responses against the clade B consensus sequence in individuals with acute (n = 10), early (n = 19) and...

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Identifiers

PMID: 15199314
DOI: 10.1097/01.aids.0000131329.51633.a3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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