Article
Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin.
Molecular and cellular biology - 1 Jul 2004
Wang XiaoZhe, Andreassen Paul R, D'Andrea Alan D
Abstract excerpt
Fanconi anemia (FA) is an autosomal recessive cancer susceptibility syndrome with at least 11 complementation groups (A, B, C, D1, D2, E, F, G, I, J, and L), and eight FA genes have been cloned. The FANCD1 gene is identical to the breast cancer susceptibility gene, BRCA2. The FA proteins cooperate in a common pathway, but the function of BRCA2/FANCD1 in this pathway remains unknown. Here we show that...
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