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Article

Polymorphisms associated with circulating sex hormone levels in postmenopausal women.

Journal of the National Cancer Institute - 16 Jun 2004

Dunning Alison M, Dowsett Mitch, Healey Catherine S, Tee Louise, Luben Robert N, Folkerd Elizabeth, Novik Karen L, Kelemen Livia, Ogata Saeko, Pharoah Paul D P, Easton Douglas F, Day N E, Ponder Bruce A J

Abstract excerpt

BACKGROUND: Reports suggest a relationship between circulating sex hormone levels and breast cancer risk, but genetic association studies have been inconclusive. We investigated the association between levels of sex hormones and single nucleotide polymorphisms (SNPs) in genes coding for the enzymes that regulate them. METHODS: We assayed circulating levels of estradiol, testosterone, estrone, androstenedione,...

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Topics

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Share to 17-alpha-Hydroxyprogesterone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aromatase

Share to Cytochrome P-450 CYP1B1

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Share to Gonadal Steroid Hormones

Share to Sex Hormone-Binding Globulin

Share to Steroid 17-alpha-Hydroxylase

Source

Identifiers

PMID: 15199113
DOI: 10.1093/jnci/djh167

Genes

SHBG
COMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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