Article
Variation in estrogen-related genes associated with cardiovascular phenotypes and circulating estradiol, testosterone, and dehydroepiandrosterone sulfate levels.
The Journal of clinical endocrinology and metabolism - 1 Jul 2008
Peter Inga, Kelley-Hedgepeth Alyson, Fox Caroline S, Cupples L Adrienne, Huggins Gordon S, Housman David E, Karas Richard H, Mendelsohn Michael E, Levy Daniel, Murabito Joanne M
Abstract excerpt
BACKGROUND: Younger age at the onset of menopause and lower circulating levels of estrogen are risk factors for cardiovascular disease. Several studies have detected associations between variations in genes encoding estrogen receptors alpha (ESR1) and beta (ESR2), and enzyme aromatase (CYP19A1), which regulates the estrogen to testosterone ratio, and cardiovascular phenotypes in the Framingham Heart Study. To...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.