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Article

Genetic polymorphisms are associated with serum levels of sex hormone binding globulin in postmenopausal women.

BMC medical genetics - 17 Dec 2008

Riancho José A, Valero Carmen, Zarrabeitia María T, García-Unzueta María T, Amado José A, González-Macías Jesús

Abstract excerpt

BACKGROUND: Estrogen activity plays a critical role in bone homeostasis. The serum levels of sex hormone binding globulin (SHBG) influence free estrogen levels and activity on target tissues. The objective of this study was to analyze the influence of common polymorphisms of the SHBG gene on serum SHBG, bone mineral density (BMD), and osteoporotic fractures. METHODS: Four biallelic polymorphisms of the SHBG gene...

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Source

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Identifiers

PMID: 19091090
DOI: 10.1186/1471-2350-9-112
PMCID: PMC2615755

Genes

SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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