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Article

The controversial association of ABCB1 polymorphisms in refractory epilepsy: an analysis of multiple SNPs in an Irish population.

Epilepsy research - 1 Feb 2007

Shahwan Amre, Murphy Kevin, Doherty Colin, Cavalleri Gianpiero L, Muckian Clare, Dicker Pat, McCarthy Mary, Kinirons Peter, Goldstein David, Delanty Norman

Abstract excerpt

Controversy has surrounded the reported association of the single nucleotide polymorphism (SNP) C3435T of the ATP-binding cassette subfamily B member 1 (ABCB1, MDR1) gene, with refractory epilepsy. Here we examine this question by: (1) attempting to replicate the original association, (2) assessing the association of other variants in high linkage disequilibrium (LD) with C3435T, and (3) evaluating and comparing...

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Source

Identifiers

PMID: 17125969
DOI: 10.1016/j.eplepsyres.2006.10.004

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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