Article
ABCB1 C3435T polymorphism influences the risk for Alzheimer's disease.
Journal of molecular neuroscience : MN - 1 Dec 2014
Fehér Ágnes, Juhász Anna, Pákáski Magdolna, Kálmán János, Janka Zoltán
Abstract excerpt
To evaluate the association of ATP-binding cassette subfamily B member 1 (ABCB1) genetic variants with the susceptibility to Alzheimer's disease (AD), we genotyped the rs1128503 (C1236T), rs2032582 (G2677T/A), and rs1045642 (C3435T) polymorphisms in a case-control sample (234 AD patients, 225 controls). Single-marker analyses revealed a significant association solely for the rs1045642 polymorphism (C/C genotype...
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