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Article

Dysregulation of the Wnt/β-Catenin Signaling Pathway in Canine Cutaneous Melanotic Tumor

31 Dec 2009

Abstract excerpt

The Wnt/beta-catenin signal transduction pathway is important in many developmental processes and during tumorigenesis. beta-Catenin acts as a signal transducer. To investigate whether the Wnt/beta-catenin signal transduction pathway is involved in canine cutaneous melanomagenesis, 18 formalin-fixed paraffin-embedded canine cutaneous melanotic tumor tissues were examined. For cloning and sequencing of the...

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PMID: 20139375
DOI: 10.1177/0300985809359303

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