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Article

MSX1 cooperates with histone H1b for inhibition of transcription and myogenesis.

Science (New York, N.Y.) - 11 Jun 2004

Lee Hansol, Habas Raymond, Abate-Shen Cory

Abstract excerpt

During embryogenesis, differentiation of skeletal muscle is regulated by transcription factors that include members of the Msx homeoprotein family. By investigating Msx1 function in repression of myogenic gene expression, we identified a physical interaction between Msx1 and H1b, a specific isoform of mouse histone H1. We found that Msx1 and H1b bind to a key regulatory element of MyoD, a central regulator of...

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Source

Identifiers

PMID: 15192231
DOI: 10.1126/science.1098096

Genes

MSX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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