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Article

Development of a BRET2 screening assay using beta-arrestin 2 mutants.

Journal of biomolecular screening - 1 Jun 2004

Vrecl Milka, Jorgensen Rasmus, Pogacnik Azra, Heding Anders

Abstract excerpt

This study has focused on enhancing the signal generated from the interaction between a G-protein-coupled receptor (GPCR) and beta-arrestin 2 (beta-arr2), measured by the bioluminescence resonance energy transfer (BRET(2)) technology. Both class A (beta(2)-adrenergic receptor [beta(2)-AR]) and class B (neurokinin-type 1 receptor [NK1-R]) GPCRs, classified based on their internalization characteristics, have been...

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Identifiers

PMID: 15191649
DOI: 10.1177/1087057104263212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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