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Spontaneous and radiation-induced chromosomal instability and persistence of chromosome aberrations after radiotherapy in lymphocytes from prostate cancer patients.

Radiation and environmental biophysics - 1 Mar 2010

Hille Andrea, Hofman-Hüther Hana, Kühnle Elna, Wilken Barbara, Rave-Fränk Margret, Schmidberger Heinz, Virsik Patricia

Abstract excerpt

The aim of the study was to compare the spontaneous and ex vivo radiation-induced chromosomal damage in lymphocytes of untreated prostate cancer patients and age-matched healthy donors, and to evaluate the chromosomal damage, induced by radiotherapy, and its persistence. Blood samples from 102 prostate cancer patients were obtained before radiotherapy to investigate the excess acentric fragments and dicentric...

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Identifiers

PMID: 19760427
DOI: 10.1007/s00411-009-0244-x
PMCID: PMC2822223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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