Article
Effects of repeated maternal separation on prepulse inhibition of startle across inbred mouse strains.
Genes, brain, and behavior - 1 Jun 2006
Millstein R A, Ralph Rebecca J, Yang Rebecca J, Holmes Andrew
Abstract excerpt
A growing body of research implicates genetic factors and childhood trauma in the etiology of neuropsychiatric diseases such as schizophrenia. However, there remains little understanding of how genetic variation influences early life stress to affect later disease susceptibility. Studies in rats have shown that postnatal maternal separation (MS) results in later deficits in prepulse inhibition of the acoustic...
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