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Article

Searching for additional disease loci in a genomic region.

Advances in genetics - 1 Jan 2008

Thomson Glenys, Barcellos Lisa F, Valdes Ana M

Abstract excerpt

Our aim is to review methods to optimize detection of all disease genes in a genetic region. As a starting point, we assume there is sufficient evidence from linkage and/or association studies, based on significance levels or replication studies, for the involvement in disease risk of the genetic region under study. For closely linked markers, there will often be multiple associations with disease, and linkage...

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PMID: 18358324
DOI: 10.1016/S0065-2660(07)00411-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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