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Article

Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2.

Pharmaceutical research - 1 May 2004

Hirouchi Masakazu, Suzuki Hiroshi, Itoda Masaya, Ozawa Shogo, Sawada Jun-ichi, Ieiri Ichiro, Ohtsubo Kenji, Sugiyama Yuichi

Abstract excerpt

PURPOSE: The presence of single nucleotide polymorphisms (SNPs) has been reported for multidrug resistance-associated protein 2 (MRP2/ABCC2). The purpose of the current study was to characterize the localization, expression level, and function of MRP2 variants. METHODS: The expression and cellular localization of the wild-type and three kinds of reported SNP variants of MRP2 molecules were analyzed in LLC-PK1...

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Source

Identifiers

PMID: 15180328
DOI: 10.1023/b:pham.0000026422.06207.33

Genes

ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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