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Article

Functional analysis of SNPs variants of BCRP/ABCG2.

Pharmaceutical research - 1 Oct 2004

Kondo Chihiro, Suzuki Hiroshi, Itoda Masaya, Ozawa Shogo, Sawada Jun-ichi, Kobayashi Daisuke, Ieiri Ichiro, Mine Kazunori, Ohtsubo Kenji, Sugiyama Yuichi

Abstract excerpt

PURPOSE: The aim of the current study was to identify the effect of single nucleotide polymorphisms (SNPs) in breast cancer resistance protein (BCRP/ABCG2) on its localization, expression level, and transport activity. METHODS: The cellular localization was identified using the wild type and seven different SNP variants of BCRP (V12M, Q141K, A149P, R163K, Q166E, P269S, and S441N BCRP) after transfection of their...

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Identifiers

PMID: 15553238
DOI: 10.1023/b:pham.0000045245.21637.d4

Genes

ABCG2
PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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