Article
Genetic polymorphisms of cytochromes P450: CYP2C9, CYP2C19, and CYP2D6 in Croatian population.
Croatian medical journal - 1 Aug 2003
Bozina Nada, Granić Paula, Lalić Zdenka, Tramisak Inja, Lovrić Mila, Stavljenić-Rukavina Ana
Abstract excerpt
AIM: To determine the prevalence of most common mutations of cytochrome P450 (CYP), ie, allelic variants of CYP2C9, CYP2C19, and CYP2D6, and to predict genotype frequency in the Croatian population. METHODS: CYP genotype was determined in 200 non-related Croatian citizens. DNA isolated from blood samples was used for the analysis of the most common allelic variants of CYP2C9, CYP2C19, and CYP2D6 by polymerase...
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