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Article

Positive and negative regulation of poly(A) nuclease.

Molecular and cellular biology - 1 Jun 2004

Mangus David A, Evans Matthew C, Agrin Nathan S, Smith Mandy, Gongidi Preetam, Jacobson Allan

Abstract excerpt

PAN, a yeast poly(A) nuclease, plays an important nuclear role in the posttranscriptional maturation of mRNA poly(A) tails. The activity of this enzyme is dependent on its Pan2p and Pan3p subunits, as well as the presence of poly(A)-binding protein (Pab1p). We have identified and characterized the associated network of factors controlling the maturation of mRNA poly(A) tails in yeast and defined its relevant...

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Identifiers

PMID: 15169912
DOI: 10.1128/MCB.24.12.5521-5533.2004
PMCID: PMC419872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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