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Article

Differential effects of aromatic and charged residue substitutions in the RNA binding domains of the yeast poly(A)-binding protein.

Journal of molecular biology - 30 May 1997

Deardorff J A, Sachs A B

Abstract excerpt

The yeast poly(A)-binding protein (Pab1p) contains four RNA recognition motifs (RRMs). Site-directed mutations were introduced into each of these RRMs in order to investigate their relative contributions to specific and non-specific RNA binding, and to determine the consequences of these mutations on the ability of Pab1p to support viability. Specifically, a charged and an aromatic residue that were predicted to...

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Source

Identifiers

PMID: 9193001
DOI: 10.1006/jmbi.1997.1013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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