Article

Direct and indirect consequences of <i>PAB1</i> deletion in the regulation of translation initiation, translation termination, and mRNA decay

2023-06-01

Abstract excerpt

<h4>ABSTRACT</h4> Cytoplasmic poly(A)-binding protein (PABPC; Pab1 in yeast) is thought to be involved in multiple steps of post-transcriptional control, including translation initiation, translation termination, and mRNA decay. To understand these roles of PABPC in more detail for endogenous mRNAs, and to distinguish its direct effects from indirect effects, we have employed RNA-Seq and Ribo-Seq to analyze chang...

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Literature Corpus work: e954acd6-95a5-571e-8008-b68ea025e5a7
DOI: 10.1101/2023.05.31.543082

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