Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation.

doi:10.1128/MCB.18.11.6548

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Article

Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation.

Molecular and cellular biology - 1 Nov 1998

Brown C E, Sachs A B

Abstract excerpt

We report that newly synthesized mRNA poly(A) tails are matured to precise lengths by the Pab1p-dependent poly(A) nuclease (PAN) of Saccharomyces cerevisiae. These results provide evidence for an initial phase of mRNA deadenylation that is required for poly(A) tail length control. In RNA 3'-end p...

Topics

Exoribonucleases
Fungal Proteins
Gene Expression Regulation, Fungal
Microfilament Proteins
Mutation
Poly A
RNA Processing, Post-Transcriptional
RNA, Messenger
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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