Article
The TALE homeodomain protein Pbx2 is not essential for development and long-term survival.
Molecular and cellular biology - 1 Jun 2004
Selleri Licia, DiMartino Jorge, van Deursen Jan, Brendolan Andrea, Sanyal Mrinmoy, Boon Elles, Capellini Terence, Smith Kevin S, Rhee Joon, Pöpperl Heike, Grosveld Gerard, Cleary Michael L
Abstract excerpt
Pbx2 is one of four mammalian genes that encode closely related TALE homeodomain proteins, which serve as DNA binding partners for a subset of Hox transcription factors. The expression and contributions of Pbx2 to mammalian development remain undefined, in contrast to the essential roles recently established for family members Pbx1 and Pbx3. Here we report that Pbx2 is widely expressed during embryonic...
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