Article
Maternal Cdx2 is dispensable for mouse development.
Development (Cambridge, England) - 1 Nov 2012
Blij Stephanie, Frum Tristan, Akyol Aytekin, Fearon Eric, Ralston Amy
Abstract excerpt
In many invertebrate and vertebrate species, cell fates are assigned through the cellular inheritance of differentially localized maternal determinants. Whether mammalian embryogenesis is also regulated by deterministic mechanisms is highly controversial. The caudal domain transcription factor CDX2 has been reported to act as a maternal determinant regulating cell fate decisions in mouse development. However,...
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