Article
The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2009
Mao Mao, Thedens Daniel R, Chang Bo, Harris Belinda S, Zheng Qing Yin, Johnson Kenneth R, Donahue Leah Rae, Anderson Michael G
Abstract excerpt
Podosome-type adhesions are actin-based membrane protrusions involved in cell-matrix adhesion and extracellular matrix degradation. Despite growing knowledge of many proteins associated with podosome-type adhesions, much remains unknown concerning the function of podosomal proteins at the level of the whole animal. In this study, the spontaneous mouse mutant nee was used to identify a component of podosome-type...
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