Article
Pbx3 deficiency results in central hypoventilation.
The American journal of pathology - 1 Oct 2004
Rhee Joon Whan, Arata Akiko, Selleri Licia, Jacobs Yakop, Arata Satoru, Onimaru Hiroshi, Cleary Michael L
Abstract excerpt
Pbx proteins comprise a family of TALE (three amino acid loop extension) class homeodomain transcription factors that are implicated in developmental gene expression through their abilities to form hetero-oligomeric DNA-binding complexes and function as transcriptional regulators in numerous cell types. We demonstrate here that one member of this family, Pbx3, is expressed at high levels predominantly in the...
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