Article
Murine Tbx2 contains domains that activate and repress gene transcription.
Gene - 23 Jan 2002
Paxton Christian, Zhao Honghua, Chin Yvette, Langner Karen, Reecy James
Abstract excerpt
T-box (Tbx) genes represent a phylogenetically conserved family of transcription factors that play important roles during embryonic development. Tbx family members have been shown to either activate or inhibit gene expression. However, little is known about the domains within Tbx proteins responsible for mediating gene transcription. While Tbx2 is known to repress gene expression, the domain(s) within Tbx2...
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