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Article

Aberrations of the p14(ARF) and p16(INK4a) genes in renal cell carcinomas.

Japanese journal of cancer research : Gann - 1 Dec 2001

Kawada Y, Nakamura M, Ishida E, Shimada K, Oosterwijk E, Uemura H, Hirao Y, Chul K S, Konishi N

Abstract excerpt

The INK4a / ARF locus on chromosome 9p21, which encodes two distinct genes, p14(ARF) and p16(INK4a), is frequently altered in human neoplasms. To investigate the potential roles of p14(ARF) and p16(INK4a) genes in human renal cell carcinomas (RCCs), we analyzed 6 human RCC cell lines and 91 primary RCCs for homozygous deletion, promoter hypermethylation and expression of the p14(ARF) and p16(INK4a) gene products...

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Share to Carcinoma, Renal Cell
Share to Chromosomes, Human, Pair 9

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to DNA Mutational Analysis

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Share to Tumor Suppressor Protein p14ARF

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Identifiers

PMID: 11749694
DOI: 10.1111/j.1349-7006.2001.tb02152.x
PMCID: PMC5926680

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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